108-09 ScienCell 重組人NOGGIN蛋白 rhNOGGIN,Recombinant Human NOGGIN
ScienCell 研究實驗室(ScienCell)是一家生物技術(shù)公司,其使命是實驗和治療用細(xì)胞和細(xì)胞相關(guān)產(chǎn)品的研究和發(fā)展。 ScienCell為研究界提供各種高質(zhì)量的正常的人類和動物細(xì)胞,細(xì)胞培養(yǎng)基和試劑,培養(yǎng)基添加因子,細(xì)胞來源的RNA,cDNA和蛋白質(zhì)。ScienCell的科學(xué)家們以改善生活質(zhì)量,實現(xiàn)細(xì)胞的能力,打擊人類退化性疾病為目的研究和開發(fā)各種細(xì)胞治療策略。ScienCell總部設(shè)在美國加利福尼亞州圣地亞哥,公司成立于1999年。
北京諾博萊德作為ScienCell品牌的特約經(jīng)銷商,為客戶提供,正規(guī)進口,貨期穩(wěn)定,折扣好的服務(wù)標(biāo)準(zhǔn)。
108-09 ScienCell重組人NOGGIN蛋白 rhNOGGIN,Recombinant Human NOGGIN,產(chǎn)品簡介:
產(chǎn)品品牌; ScienCell
產(chǎn)品貨號:108-09
產(chǎn)品名稱:108-09 ScienCell重組人NOGGIN蛋白 rhNOGGIN,Recombinant Human NOGGIN
產(chǎn)品規(guī)格:5ug
ScienCell提供純化的、高質(zhì)量的生長因子,為您的研究助力。一些專門的信號分子,在細(xì)胞的增殖和分化中發(fā)揮核心作用。只有高純度的因子才能實現(xiàn)信號通路的高強度活化。 ScienCell提供的生長因子具有以下特性:高活性,少量的蛋白即有很強效應(yīng);高純度,污染物少,干擾小。
108-09 ScienCell重組人NOGGIN蛋白 rhNOGGIN,Recombinant Human NOGGIN, 產(chǎn)品說明:
Noggin屬于一組可擴散蛋白質(zhì),它們與TGF-α家族的配體結(jié)合,并通過抑制它們進入信號受體來調(diào)節(jié)其活性。Noggin最初被確定為BMP-4拮抗劑,其作用對于頭部和其他背部結(jié)構(gòu)的正常形成至關(guān)重要。因此,Noggin已被證明可以調(diào)節(jié)其他BMP的活性,包括BMP-2,-7,-13和-14。小鼠中Noggin的靶向缺失導(dǎo)致產(chǎn)前死亡和隱性表型顯示嚴(yán)重畸形的骨骼系統(tǒng)。相反,在成熟成骨細(xì)胞中過度表達(dá)Noggin的轉(zhuǎn)基因小鼠顯示出成骨細(xì)胞分化受損,骨形成減少和嚴(yán)重的骨質(zhì)疏松癥。人類爪蟾的氨基酸序列與非洲爪蟾、大鼠和小鼠的氨基酸序列高度同源。
Noggin belongs to a group of diffusible proteins which bind to ligands of the TGF-α family and regulate their activity by inhibiting their access to signaling receptors. Noggin was originally identified as a BMP-4 antagonist whose action is critical for proper formation of the head and other dorsal structures. Consequently, Noggin has been shown to modulate the activities of other BMPs including BMP-2,-7,-13, and -14. Targeted deletion of Noggin in mice results in prenatal death and recessive phenotype displaying a severely malformed skeletal system. Conversely, transgenic mice over-expressing Noggin in mature osteoblasts display impaired osteoblastic differentiation, reduced bone formation, and severe osteoporosis. The amino acid sequence of human noggin is highly homologous to that of Xenopus, rat and mouse.
ScienCell生長添加物產(chǎn)品訂購信息:
102-01 重組人干細(xì)胞因子 rhSCF,Recombinant Human Stem Cell Factor 2ug
102-02 重組人粒細(xì)胞集落刺激因子 rhG-CSF,Recombinant Human Granulocyte Colony Stimulating Factor 2ug
102-03 重組人粒細(xì)胞巨噬細(xì)胞集落刺激因子 rhM-CSF,Recombinant Human Granulocyte Macrophage Colony Stimulating Factor 5ug
102-09 重組人巨噬細(xì)胞集落刺激因子 rhM-CSF,Recombinant Human Macrophage Colony Stimulating Factor 2ug
103-01 重組人腫瘤壞死因子-alpha rhTNF-α,Recombinant Human Tumor Necrosis Factor-alpha 10ug
103-01H 重組人腫瘤壞死因子-alpha,rhTNF--His,Recombinant Human Tumor Necrosis Factor-alpha, His 10ug
103-01v 重組人腫瘤壞死因子-alpha,Variant rhTNF-α variant,Recombinant Human Tumor Necrosis Factor-alpha Variant 10ug
103-04 重組人B細(xì)胞激活因子 rhBAFF,Recombinant Human B Cell Activating Factor 5ug
103-08 重組人制瘤素-M227a.a. rhOSM,Recombinant Human Oncostatin-M 227a.a. 2ug
103-08T 重組人制瘤素-M209a.a.,Recombinant Human Oncostatin-M209a.a 2ug
103-09 重組人血管生成抑制因子K1-3 rhAngiostatin K1-3,Recombinant Human Angiostatin K1-3 10ug
103-12 重組人血管內(nèi)皮抑制素 rhEndostatin,Recombinant Human Endostatin 20ug
104-01 重組人成纖維細(xì)胞生長因子-acidic rhaFGF,Recombinant Human Fibroblast Growth Factor-acidic 10ug
104-02 重組人成纖維細(xì)胞生長因子-basic rhbFGF,Recombinant Human Fibroblast Growth Factor-basic 10ug
104-07 重組人角質(zhì)細(xì)胞生長因子 rhKGF-1,Recombinant Human Keratinocyte Growth Factor-1 2ug
104-09 重組人成纖維細(xì)胞生長因子-9 rhFGF-9,Recombinant Human Fibroblast Growth Factor-9 5ug
104-10 重組人角質(zhì)細(xì)胞生長因子-2 rhKGF-2,Recombinant Human Keratinocyte Growth Factor-2 5ug
104-19 重組人成纖維細(xì)胞生長因子-19 rhFGF-19,Recombinant Human Fibroblast Growth Factor-19 5ug
104-21 重組人成纖維細(xì)胞生長因子-21 rhFGF-21,Recombinant Human Fibroblast Growth Factor-21 5ug
105-01 重組人胰島素生長因子-1 rhIGF-1,Recombinant Human IGF-I 20ug
105-01B 重組人DES(1-3)胰島素生長因子-1 rhIGF-BP3,Recombinant Human DES (1-3) IGF-1 20ug
105-01B3重組人胰島素生長因子-BP3,Recombinant Human IGF-BP3 5ug
105-03 重組人longR3胰島素生長因子-1 rhLR3IGF-1,Recombinant Human Long R3 Insulin-like Growth Factor-1 20ug
105-04 重組人表皮生長因子 rhEGF,Recombinant Human Epidermal Growth Factor, 100 ug 100ug
105-05 重組人血管內(nèi)皮生長因子-165 rhVEGF165,Recombinant Human VEGF165 2ug
106-06 重組人干擾素γ rhIFN-γ,Recombinant Human Interferon-gamma 20ug
107-04 重組人神經(jīng)營養(yǎng)蛋白-4 rhNT-4,Recombinant Human Neurotrophin-4 2ug
107-08 重組人纖毛神經(jīng)營養(yǎng)因子 rhCNTF,Recombinant Human Ciliary Neurotrophic Factor 5ug
107-10 重組人神經(jīng)調(diào)節(jié)蛋白 rhBTC,Recombinant Human NRG-1 EGF-like domain 10ug
107-11 重組人ErbB3片段 rhErbB3-f,Recombinant Human ErbB3 Fragment 5ug
107-12 重組人β動物纖維 rhBTC,Recombinant Human Betacellulin 5ug
108-02 重組人骨形成蛋白-2 rhBMP-2,Recombinant Human Bone Morphogenetic Protein-2 2ug
108-04 重組人骨形成蛋白-4 rhBMP-4,Recombinant Human Bone Morphogenetic Protein-4 2ug
108-07 重組人骨形成蛋白-7 rhBMP-7,Recombinant Human Bone Morphogenetic Protein-7 2ug
108-08 重組人骨保護素 rHuOPG-Fc,Recombinant Human Osteoprotegerin/Fc Chimera 10ug
108-09 重組人NOGGIN蛋白 rhNOGGIN,Recombinant Human NOGGIN 5ug
301-01 重組人生長激素 rhGF,Recombinant Human Growth Hormone 20ug