GK072 ScienCell 人類(lèi)適應(yīng)性免疫反應(yīng)qPCR檢測(cè)試劑盒,Human Adaptive Immune Response qPCR Array Kit
ScienCell 研究實(shí)驗(yàn)室(ScienCell)是一家生物技術(shù)公司,其使命是實(shí)驗(yàn)和治療用細(xì)胞和細(xì)胞相關(guān)產(chǎn)品的研究和發(fā)展。 ScienCell為研究界提供各種高質(zhì)量的正常的人類(lèi)和動(dòng)物細(xì)胞,細(xì)胞培養(yǎng)基和試劑,培養(yǎng)基添加因子,細(xì)胞來(lái)源的RNA,cDNA和蛋白質(zhì)。ScienCell的科學(xué)家們以改善生活質(zhì)量,實(shí)現(xiàn)細(xì)胞的能力,打擊人類(lèi)退化性疾病為目的研究和開(kāi)發(fā)各種細(xì)胞治療策略。ScienCell總部設(shè)在美國(guó)加利福尼亞州圣地亞哥,公司成立于1999年。
北京諾博萊德作為ScienCell品牌的經(jīng)銷(xiāo)商,為客戶提供,正規(guī)進(jìn)口,貨期穩(wěn)定,折扣好的服務(wù)標(biāo)準(zhǔn)。
GK072 ScienCell人類(lèi)適應(yīng)性免疫反應(yīng)qPCR檢測(cè)試劑盒,Human Adaptive Immune Response qPCR Array Kit,產(chǎn)品簡(jiǎn)介:
產(chǎn)品品牌: ScienCell
產(chǎn)品貨號(hào):GK072
產(chǎn)品名稱:GK072 ScienCell人類(lèi)適應(yīng)性免疫反應(yīng)qPCR檢測(cè)試劑盒,Human Adaptive Immune Response qPCR Array Kit
產(chǎn)品規(guī)格:One 96-well plate, one 20ul reaction per well
GK072 ScienCell人類(lèi)適應(yīng)性免疫反應(yīng)qPCR檢測(cè)試劑盒,Human Adaptive Immune Response qPCR Array Kit, 產(chǎn)品說(shuō)明:
ScienCell的GeneQuery™人類(lèi)適應(yīng)性免疫反應(yīng)qPCR陣列(GQH-AIR)有助于對(duì)參與適應(yīng)性免疫或獲得性免疫的88個(gè)關(guān)鍵基因進(jìn)行基因表達(dá)分析。 脊椎動(dòng)物有兩個(gè)主要的免疫系統(tǒng):先天性和適應(yīng)性。 雖然先天免疫系統(tǒng)通常負(fù)責(zé)宿主防御病原體,但適應(yīng)性免疫系統(tǒng)負(fù)責(zé)防御特定病原體,從而賦予免疫記憶。 如何根據(jù)其在適應(yīng)性免疫反應(yīng)中的功能對(duì)所包含的基因進(jìn)行分組的簡(jiǎn)要示例如下所示:
抗原呈遞:CANX、HLA-A、HLA-DPB1、PSMB8、TAP2
Th1標(biāo)志物:IL12RB1,CCR5,CD94,CXCR3。IL18R
Th2 標(biāo)志物:IL13、IL1R1、IL4、CCR8、CSF2
Th17 標(biāo)記: CCR6, IL17A, IL6, RORC, IRF4
Treg 標(biāo)記物:FOXP3、CD4、IL10、IL2RA、CTLA4
GeneQuery™ qPCR 芯片試劑盒采用 96 孔板格式的 qPCR 就緒,每個(gè)孔包含一個(gè)引物組,可識(shí)別并有效擴(kuò)增特定靶基因的 cDNA。精心設(shè)計(jì)的引物確保:(i)qPCR分析中的優(yōu)良退火溫度為65°C(含2 mM Mg2+且不含DMSO);(ii)除非另有說(shuō)明,否則引物集可識(shí)別靶基因的所有已知轉(zhuǎn)錄本變體;(iii)只有一個(gè)基因被擴(kuò)增。每個(gè)引物組都已通過(guò)qPCR和熔解曲線分析和凝膠電泳進(jìn)行了驗(yàn)證。
ScienCell's GeneQuery™ Human Adaptive Immune Response qPCR Array (GQH-AIR) facilitates gene expression profiling of 88 key genes involved in adaptive immunity or acquired immunity. Vertebrates have two main immune systems: innate and adaptive. While the innate immune system is responsible for host defense against pathogens in a general way, the adaptive immune system is responsible for defense against particular pathogens, thereby conferring immunological memory. Brief examples of how included genes may be grouped according to their function in the adaptive immune response are shown below:
· Antigen presentation: CANX, HLA-A, HLA-DPB1, PSMB8, TAP2
· Th1 markers: IL12RB1, CCR5, CD94, CXCR3. IL18R
· Th2 markers: IL13, IL1R1, IL4, CCR8, CSF2
· Th17 markers: CCR6, IL17A, IL6, RORC, IRF4
· Treg markers: FOXP3, CD4, IL10, IL2RA, CTLA4
GeneQuery™ qPCR array kits are qPCR ready in a 96-well plate format, with each well containing one primer set that recognizes and efficiently amplifies a specific target gene's cDNA. The carefully designed primers ensure that: (i) the optimal annealing temperature in qPCR analysis is 65°C (with 2 mM Mg2+and no DMSO); (ii) the primer set recognizes all known transcript variants of the target gene, unless otherwise noted; and (iii) only one gene is amplified. Each primer set has been validated by qPCR with melt curve analysis and gel electrophoresis.
GeneQuery™ 人類(lèi)適應(yīng)性免疫應(yīng)答 qPCR 陣列板布局*(8 個(gè)粗體和斜體對(duì)照)
1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | |
A | ABCC1 | CCR8 | CD40LG | FOXP3 | HLA-DQA1 | IL12RB1 | IL1R1 | IRF4 | NOTCH3 | PTPRC | STAT6 | β-actin |
B | ARG1 | CD19 | CD80 | GATA3 | HLA-DQB1 | IL12RB2 | IL1R2 | ITGAM | PDIA3 | RAG1 | TAP2 | GAPDH |
C | CANX | CD27 | CD86 | HAVCR2 | HLA-DRA | IL13 | IL2 | JAK3 | PSMB8 | RAG2 | TBX21 | LDHA |
D | CCL5 | CD28 | CSF2 | HLA-A | HLA-DRB1 | IL17A | IL2RA | KLRD1 | PSMB9 | RORA | TNF | NONO |
E | CCR1 | CD3D | CTLA4 | HLA-B | HLA-DRB3 | IL17B | IL4 | LGALS1 | PSME1 | RORC | TNFRSF4 | PPIH |
F | CCR4 | CD3E | CXCR3 | HLA-C | IFNG | IL17C | IL5 | LTA | PSME2 | STAT1 | TNFSF11 | GDC |
G | CCR5 | CD3G | CXCR4 | HLA-DPA1 | IL10 | IL18 | IL6 | MS4A1 | PSME3 | STAT3 | TRAT1 | PPC |
H | CCR6 | CD4 | CXCR6 | HLA-DPB1 | IL12A | IL18R1 | IL9 | NFKB1 | PTGDR2 | STAT4 | ZAP70 | NTC |
提示:基因選擇可能會(huì)根據(jù)新的研究和開(kāi)發(fā)進(jìn)行更新
ScienCell基因表達(dá)分析產(chǎn)品訂購(gòu)信息:
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GK002 人類(lèi)多能干細(xì)胞qPCR檢測(cè)試劑盒,Human Pluripotent Stem Cell qPCR Array Kit
GK003 人類(lèi)細(xì)胞周期qPCR檢測(cè)試劑盒,Human Cell Cycle qPCR Array Kit
GK005 人上皮細(xì)胞生物學(xué)qPCR檢測(cè)試劑盒,Human Epithelial Cell Biology qPCR Array Kit
GK006 人類(lèi)神經(jīng)發(fā)育和再生qPCR檢測(cè)試劑盒,Human Neural Development and Regeneration qPCR Array Kit
GK007 人類(lèi)神經(jīng)可塑性qPCR檢測(cè)試劑盒,Human Neural Plasticity qPCR Array Kit
GK008 人類(lèi)神經(jīng)傳遞和膜轉(zhuǎn)運(yùn)qPCR檢測(cè)試劑盒,Human Neural Transmission and Membrane Trafficking qPCR Array Kit
GK009 人類(lèi)星型膠質(zhì)細(xì)胞生物學(xué)qPCR檢測(cè)試劑盒,Human Astrocyte Cell Biology qPCR Array Kit
GK010 人類(lèi)黑素細(xì)胞發(fā)育和色素沉著qPCR檢測(cè)試劑盒,Human Melanocyte Development & Pigmentation qPCR Array Kit
GK011 人類(lèi)黑素細(xì)胞生物學(xué)qPCR檢測(cè)試劑盒,Human Melanocyte Cell Biology qPCR Array Kit
GK013 人類(lèi)星型膠質(zhì)細(xì)胞轉(zhuǎn)錄因子qPCR檢測(cè)試劑盒,Human Astrocyte Transcription Factors qPCR Array Kit
GK017 人血管生成qPCR檢測(cè)試劑盒,Human Angiogenesis qPCR Array Kit
GK018 人內(nèi)皮細(xì)胞表型異質(zhì)性qPCR檢測(cè)試劑盒,Human Endothelial Cell Phenotypic Heterogeneity qPCR Array Kit
GK019 人內(nèi)皮細(xì)胞生物學(xué)qPCR檢測(cè)試劑盒,Human Endothelial Cell Biology qPCR Array Kit
GK020 人B細(xì)胞受體信號(hào)通路qPCR檢測(cè)試劑盒,Human B Cell Receptor Signaling Pathway qPCR Array Kit
GK021 人類(lèi)T細(xì)胞受體信號(hào)通路qPCR檢測(cè)試劑盒,Human T Cell Receptor Signaling Pathway qPCR Array Kit
GK022 人內(nèi)吞作用qPCR檢測(cè)試劑盒,Human Endocytosis qPCR Array Kit
GK023 人皮內(nèi)細(xì)胞分化qPCR檢測(cè)試劑盒,Human Endothelial Cell Differentiation qPCR Array Kit
GK024 人體剪切應(yīng)力和機(jī)械傳導(dǎo)qPCR檢測(cè)試劑盒,Human Shear Stress and Mechanotransduction qPCR Array Kit
GK025 人類(lèi)Notch信號(hào)通路qPCR檢測(cè)試劑盒,uman Notch Signaling Pathway qPCR Array Kit
GK026 人類(lèi)Wnt信號(hào)通路qPCR檢測(cè)試劑盒,Human Wnt Signaling Pathway qPCR Array Kit
GK027 人類(lèi)非經(jīng)典Wnt信號(hào)通路qPCR檢測(cè)試劑盒,Human Noncanonical Wnt Signaling Pathways qPCR Array Kit
GK028 人類(lèi)Wnt信號(hào)靶基因qPCR檢測(cè)試劑盒,Human Wnt Signaling Target Genes qPCR Array Kit
GK029 Human Tie2/Angpt信號(hào)qPCR檢測(cè)試劑盒,Human Tie2/Angpt Signaling qPCR Array Kit
GK034 人肺纖維化qPCR檢測(cè)試劑盒,Human Pulmonary Fibrosis qPCR Array Kit
GK035 人體缺氧反應(yīng)qPCR檢測(cè)試劑盒,Human Hypoxia Response qPCR Array Kit
GK036 人類(lèi)HIF1信號(hào)響應(yīng)qPCR檢測(cè)試劑盒,Human HIF1 Signaling Response qPCR Array Kit
GK037 人巨噬細(xì)胞細(xì)胞生物學(xué)qPCR檢測(cè)試劑盒,Human Macrophage Cell Biology qPCR Array Kit
GK038 人類(lèi)吞噬作用qPCR檢測(cè)試劑盒,Human Phagocytosis qPCR Array Kit
GK039 人類(lèi)先天免疫反應(yīng)qPCR檢測(cè)試劑盒,Human Innate Immune Response qPCR Array Kit
GK040 人成纖維細(xì)胞生長(zhǎng)因子信號(hào)通路qPCR檢測(cè)試劑盒,Human Fibroblast Growth Factor Signaling Pathway qPCR Array Kit
GK041 人體皮膚傷口愈合qPCR檢測(cè)試劑盒,Human Skin Wound Healing qPCR Array Kit
GK056 人體止血qPCR檢測(cè)試劑盒,Human Hemostasis qPCR Array Kit
GK060 人類(lèi)晝夜節(jié)律qPCR檢測(cè)試劑盒,Human Circadian Rhythm qPCR Array Kit
GK061 人類(lèi)DNA損傷感應(yīng)qPCR檢測(cè)試劑盒,Human DNA Damage Sensing qPCR Array Kit
GK062 人類(lèi)細(xì)胞生長(zhǎng)和分裂qPCR檢測(cè)試劑盒,Human Cell Growth and Division qPCR Array Kit
GK063 人細(xì)胞周期蛋白和細(xì)胞周期蛋白依賴性激酶qPCR檢測(cè)試劑盒,Human Cyclins and Cyclin-dependent Kinases qPCR Array Kit
GK069 人類(lèi)小膠質(zhì)細(xì)胞生物學(xué)qPCR檢測(cè)試劑盒,Human Microglia Cell Biology qPCR Array Kit
GK072 人類(lèi)適應(yīng)性免疫反應(yīng)qPCR檢測(cè)試劑盒,Human Adaptive Immune Response qPCR Array Kit
GK073 人類(lèi)小膠質(zhì)細(xì)胞Sensome qPCR檢測(cè)試劑盒,Human Microglial Sensome qPCR Array Kit
GK074 人角質(zhì)細(xì)胞生物學(xué)qPCR檢測(cè)試劑盒,Human Keratocyte Biology qPCR Array
GK078 人類(lèi)神經(jīng)細(xì)胞生物學(xué)qPCR檢測(cè)試劑盒,Human Neuronal Cell Biology qPCR Array Kit
GK079 人類(lèi)軟骨細(xì)胞生物學(xué)qPCR檢測(cè)試劑盒,Human Chondrocyte Biology qPCR Array Kit
GK080 人成骨分化qPCR檢測(cè)試劑盒,GeneQuery™ Human Osteogenic Differentiation qPCR Array Kit
GK081 人類(lèi)周細(xì)胞生物學(xué)qPCR檢測(cè)試劑盒,Human Pericyte Biology qPCR Array Kit
GK084 人體軸突導(dǎo)向qPCR檢測(cè)試劑盒,Human Axon Guidance qPCR Array kit
GK087 人類(lèi)染色質(zhì)組織和重塑qPCR檢測(cè)試劑盒,Human Chromatin Organization and Remodeling qPCR Array Kit
GK088 人VEGF信號(hào)通路qPCR檢測(cè)試劑盒,Human VEGF Signaling Pathway qPCR Array Kit
GK089 人類(lèi)Ephrin信號(hào)qPCR檢測(cè)試劑盒,Human Ephrin Signaling qPCR Array Kit
GK090 人體細(xì)胞連接qPCR檢測(cè)試劑盒,Human Cell Junctions qPCR Array Kit
GK091 人肝星狀細(xì)胞生物學(xué)qPCR檢測(cè)試劑盒,Human Hepatic Stellate Cell Biology qPCR Array Kit
GK092 人胰腺星狀細(xì)胞生物學(xué)qPCR檢測(cè)試劑盒,Human Pancreatic Stellate Cell Biology qPCR Array Kit
GK093 Human Renal Mesangial Cell Biology qPCR Array Kit,Human Renal Mesangial Cell Biology qPCR Array Kit
GK094 Human Mesenchymal Stem Cell Differentiation qPCR Array,Human Mesenchymal Stem Cell Differentiation qPCR Array Kit
GK095 人間充質(zhì)至上皮細(xì)胞轉(zhuǎn)化qPCR檢測(cè)試劑盒,Human Mesenchymal to Epithelial Transition qPCR Array Kit
GK096 人類(lèi)雪旺細(xì)胞生物學(xué)qPCR檢測(cè)試劑盒,Human Schwann Cell Biology qPCR Array Kit
GK097 人類(lèi)平滑肌細(xì)胞生物學(xué)qPCR檢測(cè)試劑盒,Human Smooth Muscle Cell Biology qPCR Array Kit
GK098 人類(lèi)心臟肌細(xì)胞生物學(xué)qPCR檢測(cè)試劑盒,Human Cardiac Myocyte Biology qPCR Array Kit
GK099 人類(lèi)骨骼肌細(xì)胞生物學(xué)qPCR檢測(cè)試劑盒,Human Skeletal Muscle Cell Biology qPCR Array Kit
GK100 人角質(zhì)形成細(xì)胞生物學(xué)qPCR檢測(cè)試劑盒,Human Keratinocyte Cell Biology qPCR Array Kit
GK101 人類(lèi)Synoviocyte細(xì)胞生物學(xué)qPCR檢測(cè)試劑盒,Human Synoviocyte Cell Biology qPCR Array Kit
GK102 人類(lèi)滋養(yǎng)層細(xì)胞生物學(xué)qPCR檢測(cè)試劑盒,Human Trophoblast Cell Biology qPCR Array Kit
GK103 人前脂肪細(xì)胞生物學(xué)qPCR檢測(cè)試劑盒,Human Preadipocyte Cell Biology qPCR Array Kit
GK104 人類(lèi)細(xì)胞骨架重塑qPCR檢測(cè)試劑盒,Human Cytoskeletal Remodeling qPCR Array Kit
GK105 人類(lèi)ECM降解qPCR檢測(cè)試劑盒,Human ECM Degradation qPCR Array Kit
GK106 人類(lèi)焦點(diǎn)粘附復(fù)合物qPCR檢測(cè)試劑盒,Human Focal Adhesion Complexes qPCR Array Kit
GK107 人內(nèi)皮素信號(hào)qPCR檢測(cè)試劑盒,Human Endothelin Signaling qPCR Array Kit
GK111 人凝集素調(diào)節(jié)免疫應(yīng)答qPCR檢測(cè)試劑盒,Human Lectin Regulation in Immune Response qPCR Array Kit
GK112 人類(lèi)神經(jīng)分化標(biāo)記qPCR檢測(cè)試劑盒,Human Neural Differentiation Markers qPCR Array Kit
GK113 人類(lèi)神經(jīng)干細(xì)胞標(biāo)記qPCR檢測(cè)試劑盒,Human Neural Stem Cell Markers qPCR Array Kit
GK114 人類(lèi)小膠質(zhì)細(xì)胞極化標(biāo)記qPCR檢測(cè)試劑盒,Human Microglial Polarization Markers qPCR Array Kit
GK115 人類(lèi)骨髓譜系標(biāo)記qPCR檢測(cè)試劑盒,Human Myeloid Lineage Markers qPCR Array Kit
GK116 人B細(xì)胞和T細(xì)胞發(fā)育標(biāo)記qPCR檢測(cè)試劑盒,Human B and T Cells Development Markers qPCR Array Kit
GK117 人胸腺細(xì)胞發(fā)育標(biāo)記qPCR檢測(cè)試劑盒,Human Thymocyte Development Markers qPCR Array Kit
GK118 人類(lèi)先天淋巴細(xì)胞發(fā)育標(biāo)記qPCR檢測(cè)試劑盒,Human Innate Lymphoid Cell Development Markers qPCR Array Kit
GK119 人類(lèi)神經(jīng)祖細(xì)胞標(biāo)記qPCR檢測(cè)試劑盒,Human Neural Progenitor Markers qPCR Array Kit
GK121 人PD-1/PD-L1檢查點(diǎn)途徑qPCR檢測(cè)試劑盒,GeneQuery™ Human PD-1/PD-L1 Checkpoint Pathway qPCR Array Kit
GK123 人類(lèi)生長(zhǎng)因子qPCR檢測(cè)試劑盒,Human Growth Factors qPCR Array Kit
GK124 人類(lèi)轉(zhuǎn)錄因子qPCR檢測(cè)試劑盒,Human Transcription Factors qPCR Array Kit
GK125 人干細(xì)胞轉(zhuǎn)錄因子qPCR檢測(cè)試劑盒,Human Stem Cell Transcription Factors qPCR Array Kit
GK126 人類(lèi)細(xì)胞表面標(biāo)記qPCR檢測(cè)試劑盒,Human Cell Surface Markers qPCR Array Kit
GK127 人腦發(fā)育標(biāo)記物qPCR檢測(cè)試劑盒,Human Brain Development Markers qPCR Array Kit